Arthritis Rheum. 1976 Mar-Apr;19(2):142-9. doi: 10.1002/art.1780190203.
Many sera from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) inhibit lymphocyte-dependent antibody cytotoxicity (LDAC). RA synovial fluids also inhibit LDAC. RA serum inhibition was present in high molecular weight and 5S serum fractions, whereas in SLE it was confined to 7S fractions. A correlation between rheumatoid factor activity and LDAC inhibition was noted, and there was some evidence for inhibition of SLE serum acting on effector cells. Inhibition in RA synovial fluid was found in both high molecular weight and very low molecular weight fractions (less than 4S.)
许多类风湿性关节炎（RA）和系统性红斑狼疮（SLE）患者的血清会抑制淋巴细胞依赖性抗体细胞毒性（LDAC）。RA滑膜液也会抑制LDAC。RA血清抑制作用存在于高分子量和5S血清组分中，而在SLE中则仅限于7S组分。发现类风湿因子活性与LDAC抑制之间存在相关性，并且有一些证据表明SLE血清对效应细胞有抑制作用。在RA滑膜液中，高分子量和极低分子量组分（小于4S）均发现有抑制作用。
