链尾丝虫病：乙胺嗪治疗后人体中成年链尾双瓣线虫的退化。
Streptocerciasis: degeneration of adult Dipetalonema streptocerca in man following diethylcarbamazine therapy.
作者信息
Meyers W M, Moris R, Neafie R C, Connor D H, Bourland J
出版信息
Am J Trop Med Hyg. 1978 Nov;27(6):1137-47. doi: 10.4269/ajtmh.1978.27.1137.
PMID:569443
Abstract
Thirty-three patients in Zaire with streptocerciasis were treated daily with diethylcarbamazine (DEC) for 21 days. Histopathologic studies of biopsy specimens with papules of skin established that during DEC treatment adult male and female Dipetalonema streptocerca die and degenerate. DEC may thus produce radical cures of streptocerciasis.
摘要
在扎伊尔，33例链尾丝虫病患者每天接受乙胺嗪（DEC）治疗，为期21天。对有皮肤丘疹的活检标本进行组织病理学研究表明，在乙胺嗪治疗期间，链尾双瓣线虫的成年雌雄虫体会死亡并退化。因此，乙胺嗪可能会彻底治愈链尾丝虫病。
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