Orko R
Br J Anaesth. 1976 Mar;48(3):257-62. doi: 10.1093/bja/48.3.257.
Three groups of 50 patients were anaesthetized with diazepam 0.32 mg/kg or thiopentone 3.7 mg/kg or propanidid 4.6 mg/kg for elective carfioversion. Propanidid caused more hypotension than diazepam or thiopentone. Apnoea was most frequent following thipentone and excitatory side-effects were most prominent following propanidid; the electric countershock worsened the excitatory phenomena. The success rate of conversion was higher in the diazepam group than in the other groups, but the difference was not statistically significant. Diazepam failed to produce amnesia in about 33% of the patients. Thiopentone is suitable and pleasant for cardioversion. Diazepam is recommended in poor-risk patients and in emergency situations.
将三组每组50例患者分别用0.32毫克/千克地西泮、3.7毫克/千克硫喷妥钠或4.6毫克/千克丙泮尼地进行麻醉,以进行择期心脏复律。丙泮尼地引起的低血压比地西泮或硫喷妥钠更多。硫喷妥钠后呼吸暂停最常见,丙泮尼地后兴奋副作用最突出;电击除颤使兴奋现象加重。地西泮组的复律成功率高于其他组,但差异无统计学意义。地西泮在约33%的患者中未能产生遗忘作用。硫喷妥钠适用于心脏复律且患者感觉舒适。对于高危患者和紧急情况,推荐使用地西泮。