ABO血型系统中的遗传性“嵌合现象”。
Inherited 'mosaicism' within the ABO blood group system.
作者信息
Bird G W, Wingham J, Watkins W M, Greenwell P, Cameron A H
出版信息
J Immunogenet. 1978 Aug;5(4):215-9. doi: 10.1111/j.1744-313x.1978.tb00649.x.
A family with examples of the rare condition known as 'inherited mosaicism affecting the ABO blood groups' has been studied. In this family there were five examples of Bmos:O mosaicism. Blood group gene-specified transferase estimations were studied in this condition for the first time. In 'affected' members, levels of B gene-specified transferase were low, and amounted to only 7--10% of the activity of a normal control. It is proposed that Bmos is correctly classified as a new form of weak B.
对一个患有罕见疾病“影响ABO血型的遗传性嵌合现象”的家族进行了研究。在这个家族中有五个Bmos:O嵌合现象的实例。首次在这种情况下对血型基因指定的转移酶进行了评估。在“患病”成员中，B基因指定的转移酶水平较低，仅为正常对照活性的7%-10%。有人提出，Bmos应正确归类为弱B的一种新形式。
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