van Dijk J P, van Kreel B K
Pflugers Arch. 1978 Nov 30;377(3):217-24. doi: 10.1007/BF00584275.
Active transport of A.I.B. from mother to fetus was studied. This was done in the intact animal and using the isolated placenta, artificially perfused at both sides. It was shown that A.I.B. is actively accumulated in the placental cells. An estimate of the kinetic constants is given. It is shown that this accumulation takes place predominantly from the maternal side of the placenta. A.I.B. that has been accumulated is cleared to the maternal and fetal circulation in equal amounts. So the netto active transport from mother to fetus is brought about by an unequal distribution of carriers, the maternal side being most active.
对α-氨基异丁酸（A.I.B.）从母体到胎儿的主动转运进行了研究。这是在完整动物身上以及使用双侧人工灌注的离体胎盘进行的。结果表明，A.I.B.在胎盘细胞中被主动积累。给出了动力学常数的估计值。结果表明，这种积累主要发生在胎盘的母体一侧。积累的A.I.B.以等量清除到母体和胎儿循环中。因此，从母体到胎儿的净主动转运是由载体分布不均引起的，母体一侧最为活跃。
