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[在福尔马林溶液中长期储存期间对非无菌硬脑膜制剂生物学状况的评估]

[Assessment of the biological condition of a nonsterile preparation of cerebral dura mater during long-term storage in a formalin solution].

作者信息

Livshits L Ia, Burdeĭ G D, Gorelik M M, Ovchinnikova N M

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1978 Nov-Dec(6):46-9.

PMID:569955
Abstract

An allogeneic cerebral dura mater prepared under nonsterile conditions will become fully sterilized after 48 hours of storage in a 0.75% formalin solution. The long-term (up to 3 years) conservation of this tissue in the above mentioned solution preserves it in a condition permitting transplantation. The experimental transplantation of such tissue results in making the subdural space airtight. This occurs primarily because of the adhesion of the edges of the donor and recipients dura mater in the area of the defect as a result of aseptic inflammation with subsequent resolution and replacement of the transplant with the connective tissue of a similar structure with the dura mater.

摘要

在非无菌条件下制备的同种异体硬脑膜,在0.75%福尔马林溶液中储存48小时后将完全灭菌。将这种组织在上述溶液中长期(长达3年)保存可使其保持在允许移植的状态。这种组织的实验性移植可使硬脑膜下腔密封。这主要是由于供体和受体硬脑膜边缘在缺损区域因无菌性炎症而粘连,随后炎症消退,移植组织被与硬脑膜结构相似的结缔组织替代。

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