Galli G, Paoletti E G, Weiss J F
Science. 1968 Dec 27;162(3861):1495-6. doi: 10.1126/science.162.3861.1495.
Adult human brain contains cholestanol and two series of cholesterol precursors having 30, 29, 28, and 27 carbon atoms; one has an unsaturated steroid nucleus, and the other is unsaturated in both nucleus and side chain. The ability of preparations of brain to incorporate a specific precursor into cholesterol, as well as into these sterol metabolites in vitro, indicates that cholesterol synthesis continues long after brain maturation ceases.
成年人类大脑含有胆甾烷醇以及两个系列的胆固醇前体，这些前体含有30、29、28和27个碳原子；一个具有不饱和甾体核，另一个在核和侧链中均不饱和。大脑制剂在体外将特定前体掺入胆固醇以及这些甾醇代谢物的能力表明，在大脑成熟停止后很长时间胆固醇合成仍在继续。
