Greenland P, Murphy G W
Chest. 1979 Feb;75(2):182-3. doi: 10.1378/chest.75.2.182.
This report describes a patient with hypertrophic obstructive cardiomyopathy complicated by acute aortic and probably mitral valvular incompetence caused by endocarditis due to Staphylococcus aureus. Following the onset of valvular insufficiency, this patient developed hypotension and pulmonary edema and eventually underwent cardiac surgery in an attempt to control these complications. We review the unique pathophysiology of hypertrophic obstructive cardiomyopathy and its alterations in the presence of acute valvular incompetence and analyze the limitations of medical management of cardiac decompensation in patients with this combination of cardiac abnormalities. The possible need for early surgery in such patients is examined.
本报告描述了一名患有肥厚型梗阻性心肌病的患者,该患者并发急性主动脉瓣反流,可能还有二尖瓣反流,病因是金黄色葡萄球菌引起的感染性心内膜炎。在出现瓣膜功能不全后,该患者出现低血压和肺水肿,最终接受了心脏手术,试图控制这些并发症。我们回顾了肥厚型梗阻性心肌病的独特病理生理学及其在急性瓣膜功能不全情况下的变化,并分析了这种心脏异常组合患者心脏失代偿的药物治疗局限性。探讨了此类患者早期手术的必要性。