Bindon B M, Blanc M R, Pelletier J, Terqui M, Thimonier J
J Reprod Fertil. 1979 Jan;55(1):15-25. doi: 10.1530/jrf.0.0550015.
Plasma hormone concentrations before and during luteolysis (induced by injection of a prostaglandin analogue on Day 10 or 11 of the cycle), during the period of preovulatory follicle growth and ovulation were examined in sheep with known differences in ovulation rate (Romanov, Préalpes, Romanov x Préalpes cross, Ile de France). The number of CL at the time of treatment and the ovulation rate in the ensuing cycle were established by endoscopy. Plasma concentrations of FSH, LH, progesterone and total oestrogen were measured by radioimmunoassays in the 3 days before PG injection, then hourly for the 24 h after PG injection and 2-hourly for a further period up to about 100 h after PG injection. The onset and duration of oestrus were also recorded. Although breed differences were observed for many of the features studied, only the intervals between oestrus and the LH peak and between PG injection and the LH peak were significantly correlated with ovulation rate.
在排卵率存在已知差异的绵羊（罗曼诺夫羊、普雷阿尔普斯羊、罗曼诺夫羊与普雷阿尔普斯羊的杂交羊、法兰西岛羊）中，检测了黄体溶解前及黄体溶解期间（在周期的第10天或第11天注射前列腺素类似物诱导）、排卵前卵泡生长和排卵期间的血浆激素浓度。通过内窥镜检查确定治疗时黄体的数量以及随后周期的排卵率。在注射PG前3天通过放射免疫测定法测量FSH、LH、孕酮和总雌激素的血浆浓度，然后在注射PG后的24小时内每小时测量一次，并在注射PG后长达约100小时的进一步时间段内每2小时测量一次。还记录了发情的开始和持续时间。尽管在所研究的许多特征中观察到了品种差异，但只有发情与LH峰值之间以及PG注射与LH峰值之间的间隔与排卵率显著相关。
