Acritopoulou S, Haresign W, Foster J P, Lamming G E
J Reprod Fertil. 1977 Mar;49(2):337-40. doi: 10.1530/jrf.0.0490337.
Plasma progesterone and LH concentrations were monitored throughout a natural oestrous cycle in 12 Clun Forest ewes and compared to those following treatment with a single i.m. injection of 100 microng ICI 80,996, an analogoue of prostaglandin F-2alpha, given during the luteal phase of the cycle. After injection of the analogue there was a high degree of synchrony in the return of oestrus (440 +/- 1-9 h; mean +/- S.E.M.) and the timing of the LH peak (48-5 +/- 2-0 h) from injection. There were no significant differences in the plasma progesterone concentrations or in the height and duration of the preovulatory LH peak between control and treatment cycles. The technique offers the possibility of controlled ovulation in the ewe.
在12只克伦森林母羊的一个自然发情周期内，监测其血浆孕酮和促黄体生成素（LH）浓度，并与在周期黄体期单次肌肉注射100微克前列腺素F-2α类似物ICI 80,996后的情况进行比较。注射该类似物后，发情的恢复（440±1.9小时；平均值±标准误）和注射后促黄体生成素峰值出现的时间（48.5±2.0小时）高度同步。对照周期和处理周期之间，血浆孕酮浓度、排卵前促黄体生成素峰值的高度和持续时间均无显著差异。该技术为母羊的排卵控制提供了可能性。
