Lochmann O, Benes J, Výmola F, Pokorný J
J Hyg Epidemiol Microbiol Immunol. 1978;22(3):344-53.
Antibodies to antibiotics were studied in patients hypersensitive to these preparations and in patients with other types of allergic disease. In addition to examining these antibodies, a whole series of other immunological tests were carried out (IgG, IgA, IgM, IgE, C'3 and OPI). Antibodies to antibiotics were found in a high percentage of subjects, not only in those hypersensitive to antibiotics but also in patients with asthma bronchiale and rhinitis pollinosa. The considerable differences in IgG and IgE observed in patients with high titres of haemagglutinating antibodies to antibiotics point out the blocking character of these antibodies.
在对这些制剂过敏的患者以及患有其他类型过敏性疾病的患者中研究了抗生素抗体。除了检测这些抗体外，还进行了一系列其他免疫学检测（IgG、IgA、IgM、IgE、C'3和OPI）。不仅在对抗生素过敏的患者中，而且在支气管哮喘和花粉症患者中，都发现有高比例的受试者存在抗生素抗体。在对抗生素血凝抗体滴度高的患者中观察到的IgG和IgE的显著差异表明了这些抗体的封闭特性。
