用于流行病学调查的雷氏变形杆菌O血清分型系统的评估
Evaluation of a Proteus rettgeri O-serotyping system for epidemiological investigation.
作者信息
Penner J L, Hinton N A, Hennessy J N
出版信息
J Clin Microbiol. 1976 Apr;3(4):385-9. doi: 10.1128/jcm.3.4.385-389.1976.
An evaluation of the serotyping system for Proteus rettgeri has been performed through its application to 561 human isolates of this species. Of these, 545 were typable and could be separated into 58 O serotypes. A group of isolates from one hospital, and clinically implicated in cross-infections, was found to belong the same O serotype, confirming the clinical findings. Isolates with more than one specificity of thermostable antigen, in most cases, were found to have combinations of such specificities restricted to combinations previously defined for the O-type strains. Furthermore, the use of pooled antisera was investigated and system of pooling was devised to retain the specificity of the system and to increase the facility of the typing procedure.
通过将变形普罗威登斯菌血清分型系统应用于561株该菌的人体分离株，对该系统进行了评估。其中，545株可分型，可分为58个O血清型。一组来自同一家医院且临床上与交叉感染有关的分离株被发现属于同一O血清型，这证实了临床发现。在大多数情况下，发现具有不止一种耐热抗原特异性的分离株，其此类特异性的组合仅限于先前为O型菌株定义的组合。此外，还研究了混合抗血清的使用，并设计了混合系统，以保持系统的特异性并提高分型程序的便利性。
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