De Louvois J
J Clin Pathol. 1969 May;22(3):263-8. doi: 10.1136/jcp.22.3.263.
The serotype of 320 strains of Proteus mirabilis from clinical material was determined. Using 20 O antisera and four H antisera 61% of strains could be fully identified and 90% partially identified. A large number of serotypes were recognized but no difference was found between the serotype of organisms infecting the urinary tract and those from other infections. Biochemically identical organisms found in the same ward generally differed in serology. Proteus mirabilis was isolated from the faeces of 84.5% of 84 patients with urinary infection and from none of 20 normal controls. By serology and the Dienes test 61% of the organisms isolated from the urine and faeces of a single patient were identical, indicating that infection arose from the intestine. Most groups of serologically identical strains could, by the Dienes test, be further divided into a number of subtypes indicating that the strains were different and that cross infection had not been responsible for their spread. With three serological groups, however, the majority of strains belonged to a single Dienes type and it was concluded that these organisms had been spread from a common reservoir or carrier. Because of the unreliability of the Dienes test when carried out on random organisms it is suggested that reliable results can only be obtained by combining the Dienes test with serotyping.
对从临床样本中分离出的320株奇异变形杆菌的血清型进行了测定。使用20种O抗血清和4种H抗血清，61%的菌株能够得到完全鉴定，90%能够得到部分鉴定。识别出了大量血清型，但感染尿路的菌株血清型与其他感染来源的菌株血清型之间未发现差异。在同一病房中发现的生化特性相同的菌株，其血清学特性通常不同。84例尿路感染患者中，84.5%的患者粪便中分离出奇异变形杆菌，而20例正常对照者粪便中均未分离到。通过血清学检测和迪内斯试验发现，从单一患者尿液和粪便中分离出的菌株，61%是相同的，这表明感染源自肠道。通过迪内斯试验，大多数血清学特性相同的菌株组可进一步分为若干亚型，这表明这些菌株是不同的，交叉感染并非其传播原因。然而，有三个血清学组，大多数菌株属于单一迪内斯型，由此推断这些菌株是从共同的储存宿主或携带者传播而来的。由于对随机菌株进行迪内斯试验结果不可靠，因此建议只有将迪内斯试验与血清分型相结合才能获得可靠结果。
