Noriega-Guerra L, Aviles-Miranda A, de la Cadena O A, Espinosa L M, Chávez F, Pizzuto J
Am J Obstet Gynecol. 1979 Feb 15;133(4):439-48.
The obstetric and hematologic problems in 21 pregnancies of 18 patients with ATP are analyzed: one maternal and one fetal death occurred. Urinary estriol and oxytocinase were measured. Eighteen infants were born by vaginal delivery and three by cesarean section. None of the 20 liveborn infants died, but they had NIP due to the passage of maternal antibodies to the fetus. These results are compared to those reported in previous publications. The obstetric management of these patients should be individualized and carefully planned; it should not be based on the platelet count.
分析了18例患有血小板减少性紫癜(ATP)的患者21次妊娠中的产科和血液学问题:发生了1例孕产妇死亡和1例胎儿死亡。测定了尿雌三醇和催产素酶。18例婴儿经阴道分娩,3例经剖宫产。20例活产婴儿均未死亡,但因母体抗体通过胎盘传递给胎儿而出现新生儿免疫性血小板减少症(NIP)。将这些结果与先前出版物中报道的结果进行了比较。这些患者的产科管理应个体化并精心规划;不应基于血小板计数。