Faust D K, Gergis S D, Sokoll M D
Anesth Analg. 1979 Jan-Feb;58(1):33-5. doi: 10.1213/00000539-197901000-00011.
A case of possible malignant hyperthermia in a 6-month-old child is presented. Malignant hyperthermia was manifested in this patient by persistent metabolic acidosis in the intraoperative and postoperative periods, by a rapid rise in temperature with concomitant unresponsiveness in the postoperative period, and by a positive caffeine-halothane stimulation test. The malignant hyperthermia occurring in the postoperative period resolved promptly following administration of dantrolene sodium. An unusual aspect of this case is that both of the child's parents had normal CPK values and negative caffeine-halothane stimulation tests.
本文报告了一例6个月大儿童可能发生恶性高热的病例。该患者的恶性高热表现为术中及术后持续的代谢性酸中毒、术后体温迅速升高并伴有反应迟钝,以及咖啡因-氟烷刺激试验呈阳性。术后发生的恶性高热在给予丹曲林钠后迅速缓解。该病例的一个不寻常之处在于,患儿的父母肌酸磷酸激酶(CPK)值均正常,且咖啡因-氟烷刺激试验均为阴性。