O'Sullivan B M
Aust Vet J. 1979 Jan;55(1):19-21. doi: 10.1111/j.1751-0813.1979.tb09538.x.
The clinical signs and pathology of 6 field cases of a respiratory disease of horses which occurs in the coastal hinterland of south-eastern Queensland are described. The condition has occurred for many years and has been thought to have been associated with ingestion of Crofton weed (Eupatorium adenophorum). Coughing, rapid heaving respiration, decreased exercise tolerance and loss of condition were seen in affected horses. In longstanding cases fibrosis, alveolar lining cell proliferation, oedema, neutrophil infiltration and abscessation were seen. In some cases vascular thrombosis and infarction occur in the lungs. Similar signs and lesions occurred in one horse fed E. adenophorum for 8 months and early lesions in another fed the flowering stage of the plant for about 6 weeks. Lesions also developed in 2 rabbits experimentally fed the plant, but not in sheep or rats.
本文描述了在昆士兰州东南部沿海腹地发生的一种马呼吸道疾病6例野外病例的临床症状和病理变化。这种疾病已存在多年，一直被认为与摄入紫茎泽兰（Eupatorium adenophorum）有关。患病马匹出现咳嗽、呼吸急促、运动耐受力下降和身体状况变差等症状。在病程较长的病例中，可见纤维化、肺泡衬里细胞增生、水肿、中性粒细胞浸润和脓肿形成。部分病例肺部出现血管血栓形成和梗死。1匹喂食紫茎泽兰8个月的马以及另1匹喂食该植物花期约6周的马出现了类似症状和病变。2只经实验喂食该植物的兔子也出现了病变，但绵羊和大鼠未出现病变。
