Somer H, Chien S, Sung L A, Thurn A
Neurology. 1979 Apr;29(4):519-22. doi: 10.1212/wnl.29.4.519.
Duchenne erythrocytes showed increased osmotic fragility as compared to controls (p less than 0.01), but individual values overlapped with controls, and only half of the Duchenne erythrocyte values were abnormal. When the effect of the smaller mean corpuscular volume of Duchenne erythrocytes was taken into account, there was no significant difference from controls in membrane deformability, as determined by microsieving or flow channel measurements. The increased osmotic fragility suggests minor changes in erythrocyte membrane properties in Duchenne muscular dystrophy.
与对照组相比，杜兴氏肌营养不良症患者的红细胞渗透脆性增加（p小于0.01），但个体值与对照组有重叠，且只有一半的杜兴氏肌营养不良症患者红细胞值异常。当考虑到杜兴氏肌营养不良症患者红细胞平均体积较小的影响时，通过微筛或流动通道测量确定，其膜变形性与对照组无显著差异。渗透脆性增加表明杜兴氏肌营养不良症患者红细胞膜特性有轻微变化。
