Nadjmabadi M H, Rastan H, Aftandelian E
Thoraxchir Vask Chir. 1978 Dec;26(6):437-41. doi: 10.1055/s-0028-1096669.
Hemodynamic parameters were measured in 80 unselected patients prior to cardiopulmonary bypass for a variety of a operative procedures. Isovolemic blood withdrawel up to 24.7 ml/kg or 10 gms% and 30% hematocrit during sternotomy using ACD blood storage containers was carried out prior to bypass. Moderate hemodilution during bypass with postbypass autologous blood transfusion resulted in 60% of the study group not requiring homologous blood. The mean post-operative blood loss in this group was 245 ml. The remaining 40% received up to 1550 ml homologous blood with 820 ml mean post-operative blood loss. Omission or reduction of homologous blood requirement decreases the risk of shock lung, saves clotting factors and reduces strain on blood banking facilities.
在80例未经过挑选的患者进行各种手术操作的体外循环前，测量了血流动力学参数。在体外循环前，使用ACD储血容器在胸骨切开术期间进行了高达24.7 ml/kg或10 gms%的等容性血液抽取以及30%的血细胞比容稀释。体外循环期间进行适度血液稀释并在体外循环后进行自体输血，结果60%的研究组患者不需要输注异体血。该组患者术后平均失血量为245 ml。其余40%的患者接受了高达1550 ml的异体血，术后平均失血量为820 ml。减少或避免对异体血的需求可降低休克肺的风险、节省凝血因子并减轻血库设施的压力。
