Museteanu C, Welte M, Henneberg G, Haase J
J Infect Dis. 1979 Mar;139(3):320-3. doi: 10.1093/infdis/139.3.320.
The behavior of 1,072 mice that had recovered from encephalitic infection with intracerebrally injected yellow fever virus 17D and of 216 normal mice was tested in a maze and on a horizontal rod rotating around its axle. Infected animals needed more time (average, 8.90 min) to find their food in a maze than did normal animals (average, 4.37 min). Infected mice were able to stay on the rotating rod for a shorter time (average, 6.4 seconds) than were normal animals (average, 9.0 seconds). The correlation between the concentration of virus injected and the performance of the mice was confirmed by the extent of lesions found by histologic study: animals that had anatomic lesions after surviving encephalitic infection showed abnormal behavior.
对1072只经脑内注射黄热病病毒17D后从脑炎感染中康复的小鼠以及216只正常小鼠的行为进行了迷宫和绕轴旋转的水平杆测试。与正常动物（平均4.37分钟）相比，受感染动物在迷宫中找到食物所需时间更长（平均8.90分钟）。与正常动物（平均9.0秒）相比，受感染小鼠在旋转杆上停留的时间更短（平均6.4秒）。组织学研究发现的病变程度证实了注射病毒浓度与小鼠行为表现之间的相关性：在脑炎感染后存活下来且有解剖学病变的动物表现出异常行为。
