Bartova L M, Shmeleva N E, Tarkhanova I A
J Hyg Epidemiol Microbiol Immunol. 1976;20(1):121-7.
Complement consumption induced by Fab' fragments of rabbit IgG, irrespectively of their state of aggregation, requires the presence of homologous rabbit IgG. Up to a certain concentration of Fab' fragment, the amount of complement fixed is a linear function of the Fab' fragment dose, but further raising of the Fab'-fragment concentration does not result in complete complement consumption in the sample. The interaction between Fab' fragment and IgG is not strictly species specific.
兔IgG的Fab’片段诱导的补体消耗，无论其聚集状态如何，都需要同源兔IgG的存在。在Fab’片段达到一定浓度之前，补体固定量是Fab’片段剂量的线性函数，但进一步提高Fab’片段浓度并不会导致样品中的补体完全消耗。Fab’片段与IgG之间的相互作用并非严格的种属特异性。
