Tagami H, Ohi M, Aoshima T, Moriguchi M, Suzuki N, Yamada M
Arch Dermatol. 1979 Jun;115(6):740-1.
An aged man with a large scaly plaque over the left buttock was successfully treated by local heat therapy using an electric bed-warmer with a surface temperature of 46 degrees C. Clinically, the lesion involuted completely after two months of treatment. This was concomitantly confirmed by histopathological and mycological studies of biopsy specimens obtained from the lesion at an interval of several weeks. The isolated fungus strain of Fonsecaea pedrosol could grow at 37 degrees C on Sabouraud's dextrose agar, but was totally eradicated 24 hours after the culture was incubated at 46 degrees C. We consider that local heat therapy carried out under strict supervision is a quite effective treatment for chromomycosis. Moreover, it can be performed safely and without much discomfort to patients, and can yield satisfactory results in a relatively short time.
一名老年男性左侧臀部有一大块鳞屑斑块，使用表面温度为46摄氏度的电暖床进行局部热疗后成功治愈。临床上，治疗两个月后病变完全消退。这通过每隔几周从病变处获取的活检标本进行组织病理学和真菌学研究得到了证实。分离出的裴氏瓶霉真菌菌株在Sabouraud葡萄糖琼脂上能在37摄氏度生长，但在46摄氏度培养24小时后完全被根除。我们认为在严格监督下进行的局部热疗是治疗着色芽生菌病的一种非常有效的方法。此外，它可以安全地进行，给患者带来的不适也不多，并且能在相对较短的时间内取得满意的效果。
