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[含中链甘油三酯脂肪乳剂给药期间血清脂肪酸模式的变化]

[Behavior of the serum fatty acid patterns during administration of an MCT-containing fat emulsion].

作者信息

Sailer D, Berg G

出版信息

Infusionsther Klin Ernahr. 1979 Jun;6(3):171-4.

PMID:572340
Abstract

After a continuous intravenous 3-hour infusion of 500 ml fat emulsion containing MCT, composed of 25 g soybean oil and 25 g MCT oils, there was an infusion-induced increase of all fatty acids administered. The medium-chain fatty acids (C8-C12) revealed ideal steady-state conditions and were quickly eliminated after the infusion. The reaction of linoleic acid (C18:2) was not as favorable. Linoleic acid increased steadily during the infusion, and its elimination rate from the serum was delayed.

摘要

在持续静脉输注3小时含有中链甘油三酯(MCT)的500毫升脂肪乳剂后(该脂肪乳剂由25克大豆油和25克MCT油组成),输注导致所有给药脂肪酸增加。中链脂肪酸(C8 - C12)呈现出理想的稳态条件,且在输注后迅速消除。亚油酸(C18:2)的反应则不太理想。亚油酸在输注过程中稳步增加,其从血清中的消除速率延迟。

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