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[含中链甘油三酯脂肪乳剂给药期间血清脂肪酸模式的变化]

[Behavior of the serum fatty acid patterns during administration of an MCT-containing fat emulsion].

作者信息

Sailer D, Berg G

出版信息

Infusionsther Klin Ernahr. 1979 Jun;6(3):171-4.

PMID:572340
Abstract

After a continuous intravenous 3-hour infusion of 500 ml fat emulsion containing MCT, composed of 25 g soybean oil and 25 g MCT oils, there was an infusion-induced increase of all fatty acids administered. The medium-chain fatty acids (C8-C12) revealed ideal steady-state conditions and were quickly eliminated after the infusion. The reaction of linoleic acid (C18:2) was not as favorable. Linoleic acid increased steadily during the infusion, and its elimination rate from the serum was delayed.

摘要

在持续静脉输注3小时含有中链甘油三酯(MCT)的500毫升脂肪乳剂后(该脂肪乳剂由25克大豆油和25克MCT油组成),输注导致所有给药脂肪酸增加。中链脂肪酸(C8 - C12)呈现出理想的稳态条件,且在输注后迅速消除。亚油酸(C18:2)的反应则不太理想。亚油酸在输注过程中稳步增加,其从血清中的消除速率延迟。

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引用本文的文献

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Metabolic studies of a lipid emulsion containing medium-chain triglyceride in perioperative and total parenteral nutrition infusions.含中链甘油三酯的脂质乳剂在围手术期及全胃肠外营养输注中的代谢研究
World J Surg. 1986 Feb;10(1):38-46. doi: 10.1007/BF01656088.