[肾旁血管肉瘤作为致癌作用中性别二态性的一种表现]
[Pararenal angiosarcoma as a manifestation of sexual dimorphism in carcinogenesis].
作者信息
Turusov V S, Lanko N S
出版信息
Biull Eksp Biol Med. 1979 Jul;88(7):74-5.
PMID:572715
Abstract
Pararenal angiosarcoma developed in 42% of CBA male mice injected subcutaneously 1.2-dimethyl hydrazine (DMH) in a dose of 8 mg/kg body weight within 30 weeks. None of 176 CBA female mice given the same treatment developed such tumors. Histologically, the tumors represented various angiosarcomas characterized by a marked invasive growth into the renal parenchyma.
摘要
在30周内，以8毫克/千克体重的剂量皮下注射1,2 - 二甲基肼（DMH）的CBA雄性小鼠中，42%发生了肾旁血管肉瘤。接受相同处理的176只CBA雌性小鼠均未发生此类肿瘤。组织学上，这些肿瘤表现为各种血管肉瘤，其特征是显著浸润性生长至肾实质。
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