Duncan C J
Experientia. 1979 Jun 15;35(6):817-8. doi: 10.1007/BF01968270.
The actions on amphibian embryos of UV-irradiation, exposure to Li+ or exposure to ouabain show interesting parallels with their effects on spontaneous release at the presynaptic terminals of the neuromuscular junction. It is suggested that these treatments serve to raise intracellular Ca2+ ([Ca2+]i) in these examples, and that UV-promoted abnormalities in embryogenesis are a consequence of changes in [Ca2+]i at critical stages in development.
紫外线照射、暴露于Li⁺或暴露于哇巴因对两栖动物胚胎的作用，与它们对神经肌肉接头突触前终末自发释放的影响呈现出有趣的相似之处。有人提出，在这些例子中，这些处理方式会使细胞内Ca²⁺（[Ca²⁺]i）升高，并且胚胎发育过程中紫外线引发的异常是发育关键阶段[Ca²⁺]i变化的结果。
