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周期性小鼠生长中的卵母细胞中的蛋白质合成机制。一项定量电子显微镜研究。

Protein-synthesizing machinery in the growing oocyte of the cyclic mouse. A quantitative electron microscopic study.

作者信息

García R B, Pereyra-Alfonso S, Sotelo J R

出版信息

Differentiation. 1979;14(1-2):101-6. doi: 10.1111/j.1432-0436.1979.tb01017.x.

DOI:10.1111/j.1432-0436.1979.tb01017.x
PMID:573223
Abstract

A quantitative ultrastructural evaluation of the oocyte ribosomal population was carried out during the oocyte growth, bearing in mind that this period of the mouse oogenesis displays the greatest activity of ribosomal RNA synthesis. At the onset of growth almost 3/4 of the oocyte ribosomes exist as singles, these become polysomal ribosomes as growth progresses. At the same time the number of ribosomes increases. Once the major growth period has elapsed, the number of ribosomes starts to decrease just when lattice-like structures exhibiting a periodic organization begin to accumulate in the oocyte cytoplasmic matrix. Evidence, like the particulate organization of these lattices, the size of their particles, its digestion by RNase, and the time of the lattice appearance, together with data reported by several authors, allows one to suggest that near the end of the oocyte growth a great part of the ribosomes are stored in the lattices to be used during early development.

摘要

在卵母细胞生长过程中,对其核糖体群体进行了定量超微结构评估,同时要考虑到小鼠卵子发生的这一时期核糖体RNA合成活性最高。在生长开始时,几乎3/4的卵母细胞核糖体以单体形式存在,随着生长的进行,这些单体变成多聚核糖体。与此同时,核糖体数量增加。一旦主要生长阶段过去,核糖体数量开始减少,此时在卵母细胞细胞质基质中开始积累呈现周期性组织的晶格状结构。这些晶格的颗粒组织、颗粒大小、被核糖核酸酶消化的情况以及晶格出现的时间等证据,连同几位作者报告的数据,使人们能够推测,在卵母细胞生长接近尾声时,大部分核糖体被储存在晶格中,以便在早期发育过程中使用。

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Protein-synthesizing machinery in the growing oocyte of the cyclic mouse. A quantitative electron microscopic study.周期性小鼠生长中的卵母细胞中的蛋白质合成机制。一项定量电子显微镜研究。
Differentiation. 1979;14(1-2):101-6. doi: 10.1111/j.1432-0436.1979.tb01017.x.
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