Metz K G, Mastroianni L
Fertil Steril. 1979 Sep;32(3):329-34. doi: 10.1016/s0015-0282(16)44244-5.
This study was carried out to test the general belief that fimbriae should be considered almost indispensable to ovum capture. Surgical procedures, including resection of the mesotubarium superius and infundibulum tubae together with the creation of a fistula, are described. An attempt to enhance tubal patency by temporarily using estrogens is discussed. Ovum pickup was determined by flushing both tubes and the uterus 2 days following ovulation induction. The prior use of estrogens did not appear to have increased subsequent ovum pickup in control animals; on the contrary, it even seems possible that estrogens had negatively influenced pickup by the fistulas. With five fistulas, however, three recovered ova represented a pickup rate of 7% to 14% of all ova available following one human chorionic gonadotropin-induced ovulation. These figures suggest that ovum pickup by terminal ampullary fistulas is not negligible; they might indicate that absence of fimbriae offers neither good protection against pregnancy following sterilization nor a hopeless prognosis for fimbriectomy reversal when a distal patent tube is present.
本研究旨在验证一种普遍观点，即人们认为伞端对于卵子捕获几乎不可或缺。文中描述了包括切除输卵管系膜上部和输卵管漏斗部并同时造瘘的手术过程。讨论了通过临时使用雌激素来提高输卵管通畅性的尝试。在诱导排卵后2天，通过冲洗双侧输卵管和子宫来确定卵子拾取情况。在对照动物中，先前使用雌激素似乎并未增加随后的卵子拾取量；相反，雌激素甚至可能对瘘管的拾取产生了负面影响。然而，在五例瘘管中，有三例回收的卵子占一人绒毛膜促性腺激素诱导排卵后所有可用卵子的7%至14%。这些数据表明，终末壶腹瘘管的卵子拾取并非可以忽略不计；它们可能表明，没有伞端既不能很好地防止绝育后怀孕，当存在远端通畅的输卵管时，对于输卵管伞端切除术的逆转也并非预后无望。
