Ziegler D K, Hassanein R S, Kodanaz A, Meek J C
J Neurol Neurosurg Psychiatry. 1979 Aug;42(8):741-8. doi: 10.1136/jnnp.42.8.741.
Diurnal rhythm of plasma cortisol, of psychological state, and of pain was measured for two days in 25 migraine patients and eight control subjects. Fourteen of the migraine patients and none of the controls displayed either consistently high plasma cortisol or an occasional aberrant peak. Abnormal psychological findings, particularly depression, were found in the Minnesota Multiphasic Personality Inventory only in migraine patients with abnormal plasma cortisol levels. Neither psychological abnormality nor pain seemed the single cause of elevation of plasma cortisol.
对25名偏头痛患者和8名对照受试者进行了为期两天的血浆皮质醇、心理状态和疼痛的昼夜节律测量。14名偏头痛患者出现了血浆皮质醇持续升高或偶尔出现异常峰值的情况，而对照组中无人出现此类情况。仅在血浆皮质醇水平异常的偏头痛患者中，明尼苏达多项人格调查表发现了异常的心理表现，尤其是抑郁。心理异常和疼痛似乎都不是血浆皮质醇升高的单一原因。
