Ehlers R E, Jarrett P B, Kaplan A M
Dev Med Child Neurol. 1979 Oct;21(5):643-7. doi: 10.1111/j.1469-8749.1979.tb01679.x.
Mixed infections of the central nervous system occurring in children without underlying neurological disease may be more frequent than previously suspected. In this case report, a neonate whose cerebrospinal fluid culture at 24 hours showed group B streptococcus only, was found on postmortem examination at six days of age to have disseminated candidiasis with cerebral abscesses. The degree of systemic involvement in this newborn suggested intra-uterine acquired candidiasis. Early diagnosis of polymicrobic infections is difficult, but this case suggests it should be considered in patients not responding to antibiotic therapy.
在没有潜在神经疾病的儿童中，中枢神经系统混合感染可能比以前怀疑的更为常见。在本病例报告中，一名新生儿在出生24小时时脑脊液培养仅显示B组链球菌，在出生6天时尸检发现患有播散性念珠菌病并伴有脑脓肿。该新生儿全身受累程度提示为宫内获得性念珠菌病。多种微生物感染的早期诊断困难，但本病例提示，在对抗生素治疗无反应的患者中应考虑这种情况。
