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Opiate inhibition of peptide release from the neurohumoral terminals of hypothalamic neurones.

作者信息

Clarke G, Wood P, Merrick L, Lincoln D W

出版信息

Nature. 1979 Dec 13;282(5740):746-8. doi: 10.1038/282746a0.

DOI:10.1038/282746a0
PMID:574618
Abstract
摘要

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Opiate inhibition of peptide release from the neurohumoral terminals of hypothalamic neurones.阿片类物质对下丘脑神经元神经体液终末肽释放的抑制作用。
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Opioids influence neurohypophysial but not central oxytocin release following direct hyperosmotic stimulation of the supraoptic nucleus in urethane-anaesthetised rats.在氨基甲酸乙酯麻醉的大鼠中，直接高渗刺激视上核后，阿片类物质影响神经垂体而非中枢催产素的释放。
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Does acute, intense stimulation of oxytocin neurones in the supraoptic nucleus increase their content of oxytocin mRNA?
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Chronic intracerebroventricular morphine and lactation in rats: dependence and tolerance in relation to oxytocin neurones.大鼠慢性脑室内注射吗啡与泌乳：与催产素神经元相关的依赖性和耐受性
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Neurohypophysial opioids and oxytocin secretion: source of inhibitory opioids.神经垂体阿片类物质与催产素分泌：抑制性阿片类物质的来源
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Naloxone potentiates the release of oxytocin induced by systemic administration of cholecystokinin without enhancing the electrical activity of supraoptic oxytocin neurones.纳洛酮可增强由全身给予胆囊收缩素诱导的催产素释放，而不增强视上核催产素神经元的电活动。
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