Diem P, Teuscher A
Schweiz Med Wochenschr. 1979 Dec 1;109(46):1814-6.
A group of 12 diabetic patients with insulin allergy previously documented by positive skin tests have been investigated with insulin of bovine, porcine and human origin and with a synthetic human insulin (CGP 12 831). In 3 patients clearly positive skin tests were found even against CGP 12 831. In lymphocyte transformation tests performed in these 3 cases, an increase of 3H-thymidine uptake was found when Actrapid was added. No increase was observed when CGP 12 831 was added.
一组12名先前经皮肤试验阳性记录确诊为胰岛素过敏的糖尿病患者，接受了牛胰岛素、猪胰岛素、人胰岛素以及一种合成人胰岛素（CGP 12 831）的检测。在3名患者中，即使针对CGP 12 831也发现了明显阳性的皮肤试验结果。在对这3例患者进行的淋巴细胞转化试验中，加入Actrapid时发现3H-胸腺嘧啶核苷摄取增加。加入CGP 12 831时未观察到增加。
