Costa D L, Amdur M O
Am Ind Hyg Assoc J. 1979 Sep;40(9):809-15. doi: 10.1080/15298667991430334.
This study examines the effect of sub-micrometer aerosols of motor oil on the irritant potency of sulfur dioxide. The increase in pulmonary flow resistance in guinea pigs was used as the bioassay of irritant response. When administered simultaneously, both unused and used motor oil protected against the irritant response to sulfur dioxide. This protective effect was lost when the oils had been previously reacted with sulfur dioxide. The additives used in the motor oil provided an equivalent protection when dissolved in a mineral oil which alone did not protect. Pre-exposure to motor oil did not provide protection. Sulfur dioxide and motor oil given together as a pre-exposure provided protection against further exposure to sulfur dioxide.
本研究考察了机油亚微米气溶胶对二氧化硫刺激效力的影响。以豚鼠肺血流阻力增加作为刺激反应的生物测定指标。当同时给予时，未使用过的和用过的机油均可预防对二氧化硫的刺激反应。当这些机油预先与二氧化硫反应后，这种保护作用就消失了。机油中使用的添加剂溶解在单独使用时无保护作用的矿物油中时，可提供同等程度的保护。预先接触机油并不能提供保护作用。预先接触二氧化硫和机油一起可预防再次接触二氧化硫时的刺激反应。
