Dent R G, Edwards O M
Clin Endocrinol (Oxf). 1979 Jul;11(1):75-80. doi: 10.1111/j.1365-2265.1979.tb03048.x.
We have studied the effect of bromocriptine in seven patients with idiopathic oedema. Two patients were unable to tolerate the drug; the remaining five were maintained on doses of between 5 and 7.5 mg a day. Symptomatic improvement was noted in two patients and in both of these and one other there was a significant improvement in mean diurnal weight gain. The fall in free water and sodium clearance on standing was reduced by bromocriptine, but there was no significant change in the excessive fall in plasma volume.
我们研究了溴隐亭对7例特发性水肿患者的疗效。2例患者无法耐受该药物；其余5例患者每日服用5至7.5毫克的剂量。2例患者症状改善，在这2例患者以及另外1例患者中，平均日间体重增加均有显著改善。溴隐亭可减少站立时自由水和钠清除率的下降，但血浆量过度下降无显著变化。
