• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

受辐照生物体中内源性感染发展的定量规律(文献综述)

Quantitative regularities of development of endogenous infection in irradiated organism (survey of literature).

作者信息

Mal'tsev V N

出版信息

J Hyg Epidemiol Microbiol Immunol. 1979;23(2):121-8.

PMID:575379
Abstract

Statistical analysis of data from the literature and the author's own experimental results was carried out in order to reveal functional dependence between the dose of irradiation and the development of endogenous infection in an irradiated organism. Direct linear dependence was established between the dose of irradiation and the severity of endogenous infection at doses causing death from the "bone-marrow" syndrome in acute radiation sickness. In the case of death from the "intestinal" syndrome, inverse linear dependence can be observed between the dose of irradiation and the culture yield of microbes from internal organs. In this case, the pathological effect on the organism is due to bacterial endotoxins formed during disintegration of microbial cells in the organism. Endogenous infection and endotoxinaemia essentially aggravate the course of acute radiation disease. The importance of endogenous infection in death of the organism is neutralized after irradiation in doses causing death "under the ray".

摘要

对文献数据和作者自身实验结果进行了统计分析,以揭示辐射剂量与受辐照生物体中内源性感染发展之间的功能依赖性。在急性放射病中,导致“骨髓”综合征死亡的剂量下,辐射剂量与内源性感染的严重程度之间建立了直接线性关系。在因“肠道”综合征死亡的情况下,可观察到辐射剂量与来自内脏器官的微生物培养产量之间呈反向线性关系。在这种情况下,对生物体的病理作用是由于生物体中微生物细胞解体过程中形成的细菌内毒素。内源性感染和内毒素血症本质上加剧了急性放射病的病程。在导致“受照致死”的剂量照射后,内源性感染在生物体死亡中的重要性被抵消。

相似文献

1
Quantitative regularities of development of endogenous infection in irradiated organism (survey of literature).受辐照生物体中内源性感染发展的定量规律(文献综述)
J Hyg Epidemiol Microbiol Immunol. 1979;23(2):121-8.
2
Quantitative relationships of the harmful effect of ionizing radiation on natural resistance of the organism to various infectious agents. Review of literature.电离辐射对机体天然抵抗力及各种感染因子有害影响的定量关系。文献综述。
J Hyg Epidemiol Microbiol Immunol. 1978;22(4):421-7.
3
Some problems of antibiotic therapy in radiation sickness.放射病抗生素治疗的若干问题。
J Hyg Epidemiol Microbiol Immunol. 1975;19(2):138-47.
4
Effect of Pseudomonas contamination or antibiotic decontamination of the GI tract on acute radiation lethality after neutron or gamma irradiation.胃肠道的铜绿假单胞菌污染或抗生素去污对中子或γ射线照射后急性辐射致死率的影响。
Radiat Res. 1985 Dec;104(3):395-405.
5
Incidence of endogenous bacterial infection in murine radiation chimeras with secondary disease.患有继发性疾病的小鼠辐射嵌合体中内源性细菌感染的发生率。
Radiat Res. 1967 Nov;32(3):581-6.
6
[The dose dependence of the development of compensatory-restorative body reactions to irradiation. The EPR method].[机体对辐射的代偿性恢复反应发展的剂量依赖性。电子顺磁共振方法]
Izv Akad Nauk SSSR Biol. 1992 Mar-Apr(2):215-33.
7
Tissue-protective effects of fullerenol C60(OH)24 and amifostine in irradiated rats.富勒醇C60(OH)24和氨磷汀对辐照大鼠的组织保护作用
Colloids Surf B Biointerfaces. 2007 Jul 1;58(1):39-43. doi: 10.1016/j.colsurfb.2007.01.005. Epub 2007 Jan 16.
8
[Effect of immobilization of mice with different radiosensitivities and shielding of part of the bone marrow on survival and spleen colony formation following irradiation].
Biull Eksp Biol Med. 1981 Nov;92(11):544-5.
9
Effect of low frequency low energy pulsing electromagnetic field (PEMF) on X-ray-irradiated mice.低频低能量脉冲电磁场(PEMF)对X射线照射小鼠的影响。
Exp Hematol. 1989 Feb;17(2):88-95.
10
Clindamycin and quinolone therapy for Bacillus anthracis Sterne infection in 60Co-gamma-photon-irradiated and sham-irradiated mice.克林霉素和喹诺酮类药物对经60钴-γ光子辐照和假辐照小鼠的炭疽芽孢杆菌斯特恩株感染的治疗作用
J Antimicrob Chemother. 2005 Dec;56(6):1074-80. doi: 10.1093/jac/dki367. Epub 2005 Oct 20.