Rolland A, Thylefors B
Tropenmed Parasitol. 1979 Dec;30(4):482-8.
In four rural West-African communities with different degrees of ocular affection the development of ocular onchocerciasis has been evaluated after three years of vector control. In the area of a successful disruption of the transmission the population with a slight degree of ocular onchocerciasis before control operations started, did not show an aggravation of the lesions. In those groups severely affected at the beginning of vector control the lesions showed no progression in the majority of the cases. The diminuition of the ocular parasite load, resulting from the reduced transmission, appears to be an important factor in the change of the incidence of blindness and severe ocular lesions attributable to onchocerciasis. Contrary to this the aggravation of ocular lesions was found to be more severe in a community situated in the area reinvaded by the vector than in those that did not experience a reinvasion of the fly.
在四个眼部感染程度不同的西非农村社区，经过三年的病媒控制后，对盘尾丝虫性眼病的发展情况进行了评估。在成功阻断传播的地区，在控制行动开始前患有轻度盘尾丝虫性眼病的人群，其病变并未加重。在病媒控制开始时受严重影响的那些群体中，大多数病例的病变并未进展。由于传播减少导致眼部寄生虫负荷降低，这似乎是盘尾丝虫病所致失明和严重眼部病变发病率变化的一个重要因素。与此相反，在病媒重新侵入地区的一个社区中，眼部病变的加重比未经历苍蝇重新侵入的社区更为严重。
