减轻新生大鼠脑的去雌性化：醋酸环丙孕酮、1,4,6-雄甾三烯-3,17-二酮及合成孕激素R5020的作用机制 - Suppr

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Attenuating the defeminization of the neonatal rat brain: mechanisms of action of cyproterone acetate, 1,4,6-androstatriene-3,17,-dione and a synthetic progestin, R5020.

作者信息

McEwen B S, Lieberburg I, Chaptal C, Davis P G, Krey L C, MacLusky N J, Roy E J

出版信息

Horm Behav. 1979 Dec;13(3):269-81. doi: 10.1016/0018-506x(79)90044-8.

DOI:10.1016/0018-506x(79)90044-8

PMID:575953

Abstract

摘要

相似文献

Attenuating the defeminization of the neonatal rat brain: mechanisms of action of cyproterone acetate, 1,4,6-androstatriene-3,17,-dione and a synthetic progestin, R5020.减轻新生大鼠脑的去雌性化：醋酸环丙孕酮、1,4,6-雄甾三烯-3,17-二酮及合成孕激素R5020的作用机制

Horm Behav. 1979 Dec;13(3):269-81. doi: 10.1016/0018-506x(79)90044-8.

Aromatization: important for sexual differentiation of the neonatal rat brain.芳香化作用：对新生大鼠大脑的性别分化至关重要。

Horm Behav. 1977 Dec;9(3):249-63. doi: 10.1016/0018-506x(77)90060-5.

Effect of an inhibitor of aromatization, 1,4,6 androstatriene-3,17-dione (ATD) on LH release and steroid binding in hypothalamus of adult female rats.芳香化酶抑制剂1,4,6-雄甾三烯-3,17-二酮（ATD）对成年雌性大鼠下丘脑促黄体生成素释放及类固醇结合的影响。

Exp Brain Res. 1986;64(3):407-10. doi: 10.1007/BF00340477.

Multiple actions of steroids and their antagonists.

Arch Sex Behav. 1984 Oct;13(5):497-502. doi: 10.1007/BF01541432.

Differential effects of testosterone metabolites in the neonatal period on open-field behavior and lordosis in the rat.新生期睾酮代谢产物对大鼠旷场行为和脊柱前凸的不同影响。

Horm Behav. 1979 Dec;13(3):282-92. doi: 10.1016/0018-506x(79)90045-x.

The effects of an inhibitor of aromatization (1,4,6-androstatriene-3,17-dione) and an anti-estrogen (Cl-628) on in vivo formed testosterone metabolites recovered from neonatal rat brain tissues and purified cell nuclei. Implications for sexual differentiation of the rat brain.

Brain Res. 1977 Jun 3;128(1):176-81. doi: 10.1016/0006-8993(77)90247-5.

The role of aromatization in the development of sexual behavior of the female hamster (Mesocricetus auratus).

Horm Behav. 1981 Mar;15(1):68-76. doi: 10.1016/0018-506x(81)90035-0.

Progestin binding by brain and pituitary cell nuclei and female rat sexual behavior.

Brain Res. 1978 Jan 27;140(2):360-7. doi: 10.1016/0006-8993(78)90469-9.

The effects of long-term estrogen exposure on the induction of sexual behavior and measurements of brain estrogen and progestin receptors in the female rat.

Horm Behav. 1979 Dec;13(3):301-13. doi: 10.1016/0018-506x(79)90047-3.

Antiestrogenic effect of R5020, a synthetic progestin in human breast cancer cells in culture.合成孕激素R5020在培养的人乳腺癌细胞中的抗雌激素作用。

J Clin Endocrinol Metab. 1983 Jun;56(6):1124-30. doi: 10.1210/jcem-56-6-1124.

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Testosterone in utero and at birth dictates how stressful experience will affect learning in adulthood.子宫内和出生时的睾酮水平决定了压力经历将如何影响成年后的学习。

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13955-60. doi: 10.1073/pnas.202199999. Epub 2002 Oct 1.

Sex and the developing brain: suppression of neuronal estrogen sensitivity by developmental androgen exposure.性别与发育中的大脑：发育过程中雄激素暴露对神经元雌激素敏感性的抑制作用。

Neurochem Res. 1997 Nov;22(11):1395-414. doi: 10.1023/a:1022027408234.

Sexual orientation after prenatal exposure to exogenous estrogen.产前暴露于外源性雌激素后的性取向。

Arch Sex Behav. 1985 Feb;14(1):57-77. doi: 10.1007/BF01541353.

Exp Brain Res. 1986;64(3):407-10. doi: 10.1007/BF00340477.

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