Smith M P
JAMA. 1977 Mar 7;237(10):987-8.
The number of perforated duodenal ulcers at five Seattle-area hospitals and all duodenal ulcer operations performed at three Seattle-area hospitals were studied. In the past ten years, a decline of 35% in both perforated duodenal ulcers and all duodenal ulcer surgery indicates a similar decline in the overall incidence of duodenal ulcer. These data are supported by articles in the literature, which report a declining incidence of duodenal ulcer beginning around 1955 and continuing for 20 years. This decline challenges the idea that duodenal ulcer results chiefly from the stresses of urbanization.
研究了西雅图地区五家医院的十二指肠溃疡穿孔病例数量以及西雅图地区三家医院进行的所有十二指肠溃疡手术。在过去十年中，十二指肠溃疡穿孔病例和所有十二指肠溃疡手术数量均下降了35%，这表明十二指肠溃疡的总体发病率也有类似下降。文献中的文章支持了这些数据，这些文章报道十二指肠溃疡发病率自1955年左右开始下降并持续了20年。这一下降对十二指肠溃疡主要由城市化压力导致的观点提出了挑战。
