Gustavsson S, Nyrén O
Department of Surgery, University Hospital, Uppsala, Sweden.
Ann Surg. 1989 Dec;210(6):704-9. doi: 10.1097/00000658-198912000-00003.
To establish time trends in surgical rates for peptic ulcer disease, all surgical departments in Sweden were requested to complete a questionnaire regarding elective operations for gastric and duodenal ulcers and emergency operations for ulcer perforations performed in 1956, 1966, 1976, and 1986. A total of 8558 operations were reported for these years. The incidence of elective surgery declined steadily, the rates being 72.1, 45.0, 31.9, and 10.7 per 100,000 inhabitants. The male:female ratio fell from 4.2 to 1.5:1, while the duodenal/gastric ulcer ratio remained virtually unchanged. The operation rate for perforation decreased by 50%, from 12.8 to 6.4 per 100,000 inhabitants. We conclude that there has been a dramatic decline in elective peptic ulcer surgery in Sweden that began long before the advent of fiberoptic endoscopy, highly selective vagotomy, or H2-receptor antagonists. The comparable decline in emergency procedures suggests that true changes in the incidence or severity of the disease have occurred. In the future the few patients still needing elective surgery for peptic ulcer may have to be served by a small number of specialized centers.
为了确定消化性溃疡疾病手术率的时间趋势,瑞典所有外科科室被要求填写一份关于1956年、1966年、1976年和1986年进行的胃和十二指肠溃疡择期手术以及溃疡穿孔急诊手术的调查问卷。这些年份共报告了8558例手术。择期手术的发病率稳步下降,每10万居民中的发病率分别为72.1、45.0、31.9和10.7。男女比例从4.2降至1.5:1,而十二指肠溃疡与胃溃疡的比例基本保持不变。穿孔的手术率下降了50%,从每10万居民中的12.8降至6.4。我们得出结论,瑞典择期消化性溃疡手术率大幅下降,这早在纤维内镜检查、高选择性迷走神经切断术或H2受体拮抗剂出现之前就开始了。急诊手术率的类似下降表明该疾病的发病率或严重程度确实发生了变化。未来,仍需要进行择期消化性溃疡手术的少数患者可能不得不由少数专门中心提供服务。