Niden A H, Mishkin F S, Khurana M M, Pick R
JAMA. 1977 Mar 21;237(12):1206-11. doi: 10.1001/jama.237.12.1206.
Twenty-three patients patients with clinical signs of pulmonary embolic disease and lung infiltrates were studied to determine the value of gallium citrate Ga 67 lung scan in differentiating embolic from inflammatory lung disease. In 11 patients without angiographically proved embolism, only seven had corresponding ventilation-perfusion defects compatible with inflammatory disease. In seven of these 11 patients, the gallium 67 concentration indicated inflammatory disease. In the 12 patients with angiographically proved embolic disease, six had corresponding ventilation-perfusion defects compatible with inflammatory disease. None had an accumulation of 67Ga in the area of pulmonary infiltrate. Thus, ventilation-perfusion lung scans are of limited value when lung infiltrates are present. In contrast, the accumulation of 67Ga in the lung indicates an inflammatory process. Gallium imaging can help select those patients with lung infiltrates who need angiography.
对23例有肺栓塞疾病临床体征及肺部浸润的患者进行了研究,以确定枸橼酸镓Ga 67肺扫描在鉴别栓塞性与炎性肺病方面的价值。在11例血管造影未证实有栓塞的患者中,只有7例有与炎性疾病相符的通气-灌注缺损。在这11例患者中的7例,镓67浓度提示为炎性疾病。在12例血管造影证实有栓塞性疾病的患者中,6例有与炎性疾病相符的通气-灌注缺损。肺部浸润区域均无67Ga积聚。因此,当存在肺部浸润时,通气-灌注肺扫描的价值有限。相比之下,肺内67Ga的积聚提示有炎症过程。镓显像有助于筛选出那些需要进行血管造影的肺部浸润患者。