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[早产儿呼吸窘迫的早期诊断。克莱门茨试验在胃液中的应用]

[Early diagnosis of respiratory distress in premature infants. Application of the Clements test to the gastric fluid].

作者信息

Demarquez J L, Babin J P, Galperine R I, Allain D, Martin C

出版信息

Nouv Presse Med. 1977 Feb 12;6(6):439-40.

PMID:576499
Abstract

The stomach of the newborn infant contains swallowed amniotic fluid. The gastric fluid of 66 newborn infants was placed in contact with alcohol, following the technique reported by Clements in relation to amniotic fluid. The stability of the bubbles formed after mixing correspond to the presence of surfactant. In the case of respiratory distress in a premature infant, a positive test is in favour of transient respiratory distress. Intermediate or negative results are seen essentially in the presence of idiopathic respiratory distress. Application of the Clements test to gastric fluid collected immediately after birth is an excellent mean of diagnostic orientation in the presence of early respiratory problems in a premature infant. When negative, the child should be transferred to a specialised centre in order that intermittent positive pressure therapy may be started, the effectiveness of the latter being related to how soon it is begun.

摘要

新生儿的胃里含有咽下的羊水。按照克莱门茨报告的有关羊水的技术,将66名新生儿的胃液与酒精接触。混合后形成的气泡的稳定性与表面活性剂的存在相对应。对于早产儿呼吸窘迫的情况,阳性试验支持短暂性呼吸窘迫。基本上在特发性呼吸窘迫存在时会出现中间或阴性结果。对出生后立即采集的胃液进行克莱门茨试验,是对早产儿早期呼吸问题进行诊断性定向的极佳方法。当结果为阴性时,应将患儿转至专门中心,以便开始间歇正压通气治疗,后者的有效性与开始治疗的及时性有关。

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