Armstrong D, Van Wormer D E, Gideon W P
Obstet Gynecol. 1976 Jul;48(1):35-9.
The analysis of gastric fluid from newborns for lecithin/sphingomyelin (L/S) ratio evaluation is useful in determining whether respiratory distress will follow an early delivery. Without exception, the L/S ratios obtained on 14 gastric aspirates paralleled and were slightly higher than intrapartum values obtained from corresponding amniotic fluids (5.6 vs 3.7). Of 46 normal infants, only 1 had a gastric aspirate L/S ratio less than 2:1. No false positive results were found. The obstetrician can easily obtain gastric fluid at delivery, and by ordering an L/S ratio determination, the neonatologist can have an estimation of lung surfactant levels within 2 hours after birth. In cases where true respiratory distress syndrome (RDS) must be differentiated from other problems of respiratory distress, this information can assist in the early management of patients with RDS. Even after the development of RDS, the procedure offers a prognostic tool which the clinician can use in discussing the outcome with the parents.
分析新生儿胃液中的卵磷脂/鞘磷脂（L/S）比值，有助于确定早产是否会导致呼吸窘迫。无一例外，从14份胃吸出物中测得的L/S比值与相应羊水在分娩时测得的值平行，且略高于后者（5.6比3.7）。在46名正常婴儿中，只有1名婴儿的胃吸出物L/S比值低于2:1。未发现假阳性结果。产科医生在分娩时可轻松获取胃液，通过要求测定L/S比值，新生儿科医生可在出生后2小时内估算肺表面活性物质水平。在必须将真正的呼吸窘迫综合征（RDS）与其他呼吸窘迫问题区分开来的情况下，该信息有助于对RDS患者进行早期管理。即使在RDS发生后，该检查也提供了一种预后工具，临床医生可用于与患儿家长讨论预后情况。
