血清生长激素水平与糖尿病视网膜病变对垂体切除的反应。
Serum growth hormone levels and the response of diabetic retinopathy to pituitary ablation.
作者信息
Wright A D, Kohner E M, Oakley N W, Hartog M, Joplin G F, Fraser T R
出版信息
Br Med J. 1969 May 10;2(5653):346-8. doi: 10.1136/bmj.2.5653.346.
Abstract
Serum growth hormone levels were measured during insulin tolerance tests in 36 patients after yttrium-90 pituitary implantation for diabetic retinopathy. The response of the new blood vessels was more clearly related to loss of growth hormone function than was the improvement of retinal haemorrhages and microaneurysms. The overall response of the retinopathy was greatest when growth hormone function was lost.Since the loss of growth hormone function was related to the loss of other aspects of anterior pituitary function, a unique role of growth hormone in the response of diabetic retinopathy to pituitary ablation could not be established.
摘要
在36例因糖尿病性视网膜病变接受钇-90垂体植入术的患者中，于胰岛素耐量试验期间测定了血清生长激素水平。与视网膜出血和微动脉瘤的改善相比，新生血管的反应与生长激素功能丧失的关系更为明显。当生长激素功能丧失时，视网膜病变的总体反应最为显著。由于生长激素功能丧失与垂体前叶功能其他方面的丧失有关，因此无法确定生长激素在糖尿病性视网膜病变对垂体切除反应中的独特作用。
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