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诊断性辐射造成的基因损伤。

Genetic damage from diagnostic radiation.

作者信息

Bross I D, Natarajan N

出版信息

JAMA. 1977 May 30;237(22):2399-401.

PMID:576941
Abstract

Using the data from the Tri-State Leukemia Survey and a mathematical model, the hypothesis that low levels of diagnostic radiation produce severe genetic damage that is expressed in the child of the exposed person as leukemia and other diseases is tested. It is estimated that for about 1% of the exposed persons who are affected by radiation, there is a 50-fold increase in the risk of leukemia and a five-fold increase in certain other diseases.

摘要

利用三州白血病调查的数据和一个数学模型,对低剂量诊断性辐射会产生严重基因损伤这一假设进行了检验,该损伤会在受辐射者的子女身上表现为白血病和其他疾病。据估计,在约1%受辐射影响的人群中,患白血病的风险增加50倍,患某些其他疾病的风险增加5倍。

相似文献

1
Genetic damage from diagnostic radiation.诊断性辐射造成的基因损伤。
JAMA. 1977 May 30;237(22):2399-401.
2
Preconception radiation and leukemia.孕前辐射与白血病
J Med. 1973;4(5):276-81.
3
Genetic damage from diagnostic radiation.诊断性辐射造成的基因损伤。
JAMA. 1977 Sep 5;238(10):1023-5.
4
Cumulative genetic damage in children exposed to preconception and intrauterine radiation.受孕前和宫内受辐射儿童的累积遗传损伤。
Invest Radiol. 1980 Jan-Feb;15(1):52-64. doi: 10.1097/00004424-198001000-00009.
5
Preliminary report on radiation and heart disease.辐射与心脏病初步报告
J Med. 1978;9(1):3-15.
6
Leukemia from low-level radiation: identification of susceptible children.低剂量辐射所致白血病:易感儿童的识别
N Engl J Med. 1972 Jul 20;287(3):107-10. doi: 10.1056/NEJM197207202870301.
7
[Hygienic characteristics of genetically significant doses in roentgenolopic studies].[X射线研究中遗传显著剂量的卫生学特征]
Gig Sanit. 1973 Aug;38(8):48-50.
8
Letter: Dangers of diagnostic irradiation in early pregnancy.信件:妊娠早期诊断性辐射的危害。
S Afr Med J. 1974 Jan 19;48(3):73.
9
Risk estimation for multifactorial diseases. A report of the International Commission on Radiological Protection.多因素疾病的风险评估。国际放射防护委员会报告。
Ann ICRP. 1999;29(3-4):1-144.
10
[Stochastic risk estimation from medical x-ray diagnostic examinations (author's transl)].
Nihon Igaku Hoshasen Gakkai Zasshi. 1980 Sep 25;40(9):885-97.

引用本文的文献

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Solar activity cycle and the incidence of foetal chromosome abnormalities detected at prenatal diagnosis.
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2
Direct estimates of low-level radiation risks of lung cancer at two NRC-compliant nuclear installations: why are the new risk estimates 20 to 200 times the old official estimates?对两个符合美国核管理委员会规定的核设施中肺癌低水平辐射风险的直接估计:为何新的风险估计是旧官方估计的20至200倍?
Yale J Biol Med. 1981 Sep-Oct;54(5):317-28.
3
The immune system and cancers of foetal origin.免疫系统与胎儿源性癌症。
Cancer Immunol Immunother. 1982;14(2):110-6. doi: 10.1007/BF00200178.
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A dosage response curve for the one rad range: adult risks from diagnostic radiation.一拉德剂量范围的剂量反应曲线:诊断性辐射对成年人的风险
Am J Public Health. 1979 Feb;69(2):130-6. doi: 10.2105/ajph.69.2.130.
5
Quantitative risk in radiation protection standards.辐射防护标准中的定量风险。
Radiat Environ Biophys. 1979;17(1):1-28. doi: 10.1007/BF01323117.
6
Adult leukemia following diagnostic x-rays? (Review of report by BROSS, BALL, and FALEN on a tri-state leukemia survey).诊断性X光照射后引发的成人白血病?(对布罗斯、鲍尔和法伦关于三州白血病调查的报告的综述)
Am J Public Health. 1979 Feb;69(2):137-45. doi: 10.2105/ajph.69.2.137.
7
Selection of treatment in the management of thyrotoxicosis in childhood and adolescence.儿童和青少年甲状腺毒症治疗中的治疗选择
Ann Surg. 1978 Jun;187(6):593-8. doi: 10.1097/00000658-197806000-00002.