Dihydroorotic acid dehydrogenase: introduction into erythrocyte by the malaria parasite.

Krooth R S, Wuu K D, Ma R

Science. 1969 May 30;164(3883):1073-5. doi: 10.1126/science.164.3883.1073.

Mature, circulating mammalian erythrocytes lack dihydroorotic acid dehydrogenase activity. However, we have detected activity, which appears to reside in an enzyme, in malaria parasites purified from mammalian blood.