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兔淋巴细胞的体外研究。十、含有与转化细胞供体共有的同种异型决定簇的抗同种异型血清诱导母细胞转化

Studies on rabbit lymphocytes in vitro. X. The induction of blast transformation by anti-allotypic sera that contain allotypic determinants in common with the donor of the transformed cells.

作者信息

Sell S, Gell P G

出版信息

Immunology. 1969 Feb;16(2):285-9.

PMID:5769980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1409578/
Abstract

Anti-allotypic sera that have no known allotypic determinants other than those also present in the genotype of the lymphocyte donor are as able to induce lymphocyte `blast' transformation as are anti-allotypic sera that do have allotypic determinants that are not present in the lymphocyte donor. Therefore, anti-allotypic sera do not appear to function in the stimulation of blast transformation by providing access for any of the known allotypic determinants into lymphocytes.

摘要

除淋巴细胞供体基因型中也存在的那些同种异型决定簇外没有已知同种异型决定簇的抗同种异型血清,与具有淋巴细胞供体中不存在的同种异型决定簇的抗同种异型血清一样,能够诱导淋巴细胞“母细胞”转化。因此,抗同种异型血清似乎不是通过为任何已知的同种异型决定簇进入淋巴细胞提供途径来发挥刺激母细胞转化的作用。

相似文献

1
Studies on rabbit lymphocytes in vitro. X. The induction of blast transformation by anti-allotypic sera that contain allotypic determinants in common with the donor of the transformed cells.兔淋巴细胞的体外研究。十、含有与转化细胞供体共有的同种异型决定簇的抗同种异型血清诱导母细胞转化
Immunology. 1969 Feb;16(2):285-9.
2
Studies on rabbit lymphocytes in vitro. XII. Augmentation of anti-allotypic blast transformation by a second anti-allotypic serum directed against the primary stimulating anti-allotypic serum (piggy-back effect).兔淋巴细胞的体外研究。十二、针对初次刺激的抗同种异型血清的第二种抗同种异型血清增强抗同种异型胚细胞转化(接力效应)。
J Immunol. 1970 Jan;104(1):114-8.
3
Studies on rabbit lymphocytes in vitro. XI. Superaddition of anti-allotypic lymphocyte transformation: evidence for multipotent lymphoid cells.兔淋巴细胞的体外研究。十一。抗同种异型淋巴细胞转化的叠加:多能淋巴细胞的证据。
J Immunol. 1970 Jan;104(1):103-13.
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The transformation of human lymphocytes by monkey antisera to human immunoglobulins.猴抗人免疫球蛋白对人淋巴细胞的转化作用。
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Studies on rabbit lymphocytes in vitro. 13. The induction of blast transformation with the F (ab')2 and Fab fragments of anti-lymphocytic, anti-IgG and anti-allotypic globulins.兔淋巴细胞的体外研究。13. 抗淋巴细胞、抗IgG和抗同种异型球蛋白的F(ab')2和Fab片段诱导母细胞转化
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Enhancement by reducing agents of the transformation of human and rabbit peripheral lymphocytes.还原剂对人及兔外周淋巴细胞转化的增强作用。
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Studies on rabbit lymphocytes in vitro. IX. The suppression of antiallotype-induced blast transformation in lymphocyte cultures from allotypically suppressed donors.兔淋巴细胞的体外研究。IX. 来自同种异型抑制供体的淋巴细胞培养物中抗同种异型诱导的母细胞转化的抑制
J Exp Med. 1968 Aug 1;128(2):341-55. doi: 10.1084/jem.128.2.341.
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Studies on rabbit lymphocytes in vitro. XV. The effect of blocking serum on anti-allotypic lymphocyte transformation.兔淋巴细胞的体外研究。十五。封闭血清对同种异型淋巴细胞转化的影响。
J Immunol. 1972 Mar;108(3):674-82.
9
Studies on rabbit lymphocytes in vitro. 8. The relationship between heterozygosity and homozygosity of lymphocyte donor and per cent blast transformation induced by antiallotype sera.家兔淋巴细胞的体外研究。8. 淋巴细胞供体的杂合性与纯合性以及抗同种异型血清诱导的母细胞转化百分比之间的关系。
J Exp Med. 1968 Jun 1;127(6):1139-48. doi: 10.1084/jem.127.6.1139.
10
Studies on rabbit lymphocytes in vitro. II. Induction of blast transformation with antisera to six IgG allotypes and summation with mixtures of antisera to different allotypes.兔淋巴细胞的体外研究。II. 用针对六种IgG同种异型的抗血清诱导母细胞转化以及不同同种异型抗血清混合物的累加作用
J Exp Med. 1965 Oct 1;122(4):813-21. doi: 10.1084/jem.122.4.813.

本文引用的文献

1
STUDIES ON RABBIT LYMPHOCYTES IN VITRO. I. STIMULATION OF BLAST TRANSFORMATION WITH AN ANTIALLOTYPE SERUM.家兔淋巴细胞的体外研究。I. 用抗独特型血清刺激母细胞转化
J Exp Med. 1965 Aug 1;122(2):423-40. doi: 10.1084/jem.122.2.423.
2
CHANGES INDUCED BY TUBERCULIN IN LEUCOCYTE CULTURES.结核菌素在白细胞培养物中引起的变化。
Lancet. 1963 Nov 23;2(7317):1091-4. doi: 10.1016/s0140-6736(63)92860-5.
3
Tuberculin-induced mitosis in peripheral blood leucocytes.结核菌素诱导外周血白细胞有丝分裂。
Lancet. 1963 Mar 23;1(7282):637-8. doi: 10.1016/s0140-6736(63)91275-3.
4
Serum groups in rabbits.家兔的血清型
Immunology. 1959 Jan;2(1):84-92.
5
Studies on rabbit lymphocytes in vitro. 8. The relationship between heterozygosity and homozygosity of lymphocyte donor and per cent blast transformation induced by antiallotype sera.家兔淋巴细胞的体外研究。8. 淋巴细胞供体的杂合性与纯合性以及抗同种异型血清诱导的母细胞转化百分比之间的关系。
J Exp Med. 1968 Jun 1;127(6):1139-48. doi: 10.1084/jem.127.6.1139.
6
Immunoglobulin allotypes of experimental animals.实验动物的免疫球蛋白同种异型
Prog Allergy. 1967;11:141-84.
7
Further characterization of rabbit immunoglobulin allotype Ab9.兔免疫球蛋白同种异型Ab9的进一步特性分析
Immunochemistry. 1968 Jul;5(4):401-4. doi: 10.1016/0019-2791(68)90135-3.