Goldman M, Bauer S R
Acta Endocrinol (Copenh). 1977 May;85(1):64-70. doi: 10.1530/acta.0.0850064.
The iodine concentrating ability of thyroid glands, thymus gland and skin in Sprague-Dawley rats was assessed by determining the tissue/blood radioiodide concentration ratios. Tissue/blood ratios are significantly affected by the age of the rats, however, thymus/blood radioiodide ratios never exceeded unity. The comparative uptake of 131I by thymus and thyroid tissue expressed as thymus/thyroid (%) for neonate animals was 10-16 times greater than those obtained for older rats. Moreover, the fraction of injected dose of radioiodide in thymus tissue never exceeded that of the thyroid or skin and paralleled the concentration of radio-activity in the blood. These results indicate that although neonate thymus tissue contains a significantly greater amount of radioactivity than the thymus of older rats, an active iodide concentration mechanism is not involved.
通过测定组织/血液放射性碘浓度比，评估了斯普拉格-道利大鼠甲状腺、胸腺和皮肤的碘浓缩能力。然而，组织/血液比受大鼠年龄的显著影响，胸腺/血液放射性碘比从未超过1。新生动物胸腺和甲状腺组织对131I的相对摄取量，以胸腺/甲状腺（%）表示，比老年大鼠高10 - 16倍。此外，胸腺组织中放射性碘注射剂量的比例从未超过甲状腺或皮肤，且与血液中的放射性浓度平行。这些结果表明，尽管新生胸腺组织中的放射性比老年大鼠的胸腺显著更多，但并不涉及活跃的碘浓缩机制。
