肾神经反射活动的脊髓上控制
Supraspinal control of reflex activity in renal nerves.
作者信息
Coote J H, Downman C B
出版信息
J Physiol. 1969 May;202(1):161-70. doi: 10.1113/jphysiol.1969.sp008801.
Abstract
- In anaesthetized cats distension of carotid sinus inhibited renal nerve activity and intercostal-renal nerve reflexes. The degree of inhibition was dependent on the amount of rise in sinus pressure. Intercostal-intercostal reflexes were not inhibited.2. Inhibition of renal nerve activity and intercostal-renal nerve reflexes could be obtained on stimulating in the dorsal reticular formation but mainly in the ventromedial reticular formation at the level of the obex. The intercostal reflex could also be inhibited at several of these points.3. The possibility that two inhibitory mechanisms are available is suggested, at least one projecting on to spinal reflex arcs.4. Other ways of inhibiting renal nerve activity were shown. One was similar to that produced by single shocks to peripheral skin and muscle nerves, and the other was due to a subnormal excitability of vasomotor neurones following intense activation.
摘要
在麻醉猫中，颈动脉窦扩张可抑制肾神经活动及肋间 - 肾神经反射。抑制程度取决于窦压力升高的幅度。肋间 - 肋间反射未受抑制。
刺激延髓闩部水平的背侧网状结构，尤其是腹内侧网状结构，可抑制肾神经活动及肋间 - 肾神经反射。在这些部位中的几个点也可抑制肋间反射。
提示可能存在两种抑制机制，至少有一种投射到脊髓反射弧上。
还展示了其他抑制肾神经活动的方式。一种类似于对周围皮肤和肌肉神经进行单次电击所产生的方式，另一种是由于强烈激活后血管运动神经元的兴奋性低于正常水平。
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