Tubaro E, Burberi S, Lotti B, Croce C
Arzneimittelforschung. 1977 Feb;27(2):397-9.
The xanthine oxidase increase in mice liver as response to infection was studied as a possible parameter useful for a better understanding of theimmunosuppression due to cyclophosphamide and cortisone. An impact of cortisone but not of cyclophosphamide on this mechanism was found; this may be useful in order to discriminate between the two different types of immunosuppressive drugs.
研究了小鼠肝脏中黄嘌呤氧化酶因感染而增加的情况，将其作为一个可能有助于更好理解环磷酰胺和可的松所致免疫抑制的参数。发现可的松对此机制有影响，而环磷酰胺则无；这可能有助于区分这两种不同类型的免疫抑制药物。
