组织胞浆菌病对红细胞抗原抗体反应的影响。
Effect of histoplasmosis on antibody response to an erythrocyte antigen.
作者信息
Cozad G C, Scalarone G M
出版信息
J Bacteriol. 1969 Feb;97(2):576-80. doi: 10.1128/jb.97.2.576-580.1969.
Infection of mice with Histoplasma capsulatum depressed their ability to form agglutinins against foreign erythrocytes. Animals previously inoculated with 10(8) yeast cells of H. capsulatum showed the most significant depression, occurring when erythrocytes were injected 8 days after infection. The average log(2) hemagglutinin titer was 2.7 compared to 8.0 for the control (noninfected) group. In general, depression of hemagglutinin response in all infected mice was greatest 8 days after infection, but response was back to near normal after 16 days and stayed at that level for the remaining time tested (24 days).
用荚膜组织胞浆菌感染小鼠会降低它们形成针对外来红细胞的凝集素的能力。先前接种了10⁸个荚膜组织胞浆菌酵母细胞的动物表现出最显著的抑制，这种抑制在感染后8天注射红细胞时出现。与对照组（未感染）的平均log₂血凝素滴度8.0相比，感染组的平均log₂血凝素滴度为2.7。一般来说，所有感染小鼠的血凝素反应抑制在感染后8天最为明显，但在16天后反应恢复到接近正常水平，并在剩余的测试时间（24天）内保持在该水平。
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