胎羊的低氧血症与主动脉化学感受器功能
Hypoxaemia and aortic chemoreceptor function in foetal lambs.
作者信息
Dawes G S, Duncan S L, Lewis B V, Merlet C L, Owen-Thomas J B, Reeves J T
出版信息
J Physiol. 1969 Mar;201(1):105-16. doi: 10.1113/jphysiol.1969.sp008745.
Abstract
- In foetal lambs the effect of raising and lowering arterial P(O2) (by varying the O(2) content of the maternal inspired gas mixture) was studied in order to determine whether the systemic arterial chemoreceptors regulated the circulation.2. From 0.7 of term relative hypoxaemia (e.g. reducing carotid P(O2) from 40 to 20 mm Hg) caused a rise of arterial pressure and femoral vaso-constriction. These changes were unaffected or even increased by bilateral section of the nerves from the carotid sinus and body. They were abolished by section of the vagi or aortic nerves.3. It is concluded that in foetal lambs during the last third of gestation the circulation is under reflex control by the aortic chemoreceptors.
摘要
为了确定全身动脉化学感受器是否调节循环，研究了在胎羊中升高和降低动脉血氧分压（通过改变母体吸入气体混合物中的氧含量）的影响。
从足月的0.7起，相对低氧血症（例如将颈动脉血氧分压从40毫米汞柱降至20毫米汞柱）会导致动脉压升高和股血管收缩。双侧切断来自颈动脉窦和颈动脉体的神经后，这些变化未受影响甚至增强。切断迷走神经或主动脉神经后，这些变化消失。
得出的结论是，在妊娠最后三分之一期间的胎羊中，循环受主动脉化学感受器的反射控制。
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