Flage T, Sand A B, Syrdalen P
Acta Ophthalmol (Copenh). 1977 Jun;55(3):489-96. doi: 10.1111/j.1755-3768.1977.tb06126.x.
The results from a retrospective clinical study of a group of patients with a specific macular disease are presented. The group includes young adults, otherwise healthy, with no hereditary diseases. The macular disease is as a rule monolateral. The lesion consits of a small central nodule surrounded by subretinal haemorrhages, retinal oedema and degenerative changes in the adjacent pigment epithelium. Fluorescein angiography demonstrates subretinal neovascularization in the central part of the lesion. The disease is selflimiting and the lesion develops into a fibrotic scar. In some cases, small, atrophic spots are seen scattered in the eyeground. There is no vitreous reaction and no signs of anterior uveitis. The clinical picture is identical with the macular lesion reported in the presumed ocular histoplasmosis syndrome.
本文展示了一组患有特定黄斑疾病患者的回顾性临床研究结果。该组患者包括年轻成年人,身体健康,无遗传性疾病。黄斑疾病通常为单侧性。病变由一个小的中央结节组成,周围有视网膜下出血、视网膜水肿以及相邻色素上皮的退行性改变。荧光素血管造影显示病变中央部分有视网膜下新生血管形成。该疾病具有自限性,病变会发展为纤维化瘢痕。在某些情况下,可在眼底看到散在的小萎缩斑。无玻璃体反应,也无前葡萄膜炎的迹象。临床表现与推测的眼组织胞浆菌病综合征中所报道的黄斑病变相同。